Last update 23 Nov 2024

Sivifene

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Sivifene (USAN/INN), Sivifeno, Sivifenum
+ [2]
Target
ER
Mechanism
ERs modulators(Estrogen receptors modulators)
Therapeutic Areas
NeoplasmsUrogenital DiseasesDigestive System Disorders+ [5]
Active Indication-
Inactive Indication
Anal intraepithelial neoplasiaBreast CancerKaposi Sarcoma+ [4]
Originator Organization-
Active Organization-
Inactive Organization
Kirax Corp.Kirax Corp.
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC19H14N4O6
InChIKeyYOQPCWIXYUNEET-UHFFFAOYSA-N
CAS Registry2675-35-6

Related

3
Clinical Trials associated with Sivifene
CTRI/2011/12/002265 / CompletedNot Applicable
â??Homeopathic Drug Proving study to evaluate the clinical symptoms of A-007 in healthy volunteersâ??
NCT00596258 / CompletedPhase 2
A Two-Stage Phase 2 Study Of Dose-Intense 4,4'-Dihydroxybenzophenone-2,4-Dinitrophenyl-Hydrazone (A-007) Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the Cervix
NCT00002153 / CompletedPhase 1
Topical Use of 4,4'-Dihydroxybenzophenone-2,4-Dinitrophenylhydrazone (A-007) in the Treatment of Advanced Malignancies Including Kaposi's Sarcoma and Lymphoproliferative Disorders
100 Clinical Results associated with Sivifene
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100 Translational Medicine associated with Sivifene
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100 Patents (Medical) associated with Sivifene
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100 Deals associated with Sivifene
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External Link

KEGGWikiATCDrug Bank
D09380Sivifene-
DB05686

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Anal intraepithelial neoplasiaPhase 2
US
Kirax Corp.Kirax Corp.
-
Uterine Cervical DysplasiaPhase 2
US
Kirax Corp.Kirax Corp.
-
Uterine Cervical DysplasiaPhase 2
MX
Kirax Corp.Kirax Corp.
-
Breast CancerPhase 1
US
--
Kaposi SarcomaPhase 1
US
--
LymphomaPhase 1
US
--
MelanomaPhase 1
US
--
Uterine Cervical CancerPhase 1
US
--
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Clinical Result

Indication
Phase
Evaluation
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Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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