Last update 01 Dec 2025

XM161-SN38

Overview

Basic Info

Drug Type
Peptide drug conjugates
Synonyms
XM161 SN38, XM161-01
Target
IL-13Rα2 x Top I
Action
inhibitors
Mechanism
IL-13Rα2 inhibitors(Interleukin-13 receptor subunit alpha-2 inhibitors), TOP1 inhibitors(DNA topoisomerase I inhibitors)
Therapeutic Areas
NeoplasmsNervous System DiseasesOther Diseases
Active Indication
GlioblastomaDiffuse Intrinsic Pontine Glioma
Inactive Indication-
Originator Organization
Excellamol, Inc.Excellamol, Inc.
Active Organization
DT&CRO Co., Ltd.DT&CRO Co., Ltd.Excellamol, Inc.Excellamol, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
RegulationOrphan Drug (United States)

Structure/Sequence

Molecular FormulaC22H20N2O5
InChIKeyFJHBVJOVLFPMQE-QFIPXVFZSA-N
CAS Registry86639-52-3
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Related

100 Clinical Results associated with XM161-SN38
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100 Translational Medicine associated with XM161-SN38
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100 Patents (Medical) associated with XM161-SN38
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100 Deals associated with XM161-SN38
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
GlioblastomaPreclinical
South Korea
DT&CRO Co., Ltd.DT&CRO Co., Ltd.
02 Sep 2025
GlioblastomaPreclinical
South Korea
Excellamol, Inc.Excellamol, Inc.
02 Sep 2025
Diffuse Intrinsic Pontine GliomaPreclinical
South Korea
Excellamol, Inc.Excellamol, Inc.
17 Jun 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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