Last update 08 Aug 2026

REGN15505

Overview

Basic Info

Drug Type
Bispecific antibody
Synonyms
PSMAx4-1BB bispecific antibody REGN15505, REGN15505 (PSMAx4-1BB), REGN15505
Target
4-1BB x PSMA
Action
agonists, modulators
Mechanism
4-1BB agonists(Tumor necrosis factor receptor superfamily member 9 agonists), PSMA modulators(Prostate-specific membrane antigen modulators)
Therapeutic Areas
NeoplasmsUrogenital Diseases
Active Indication
Metastatic castration-resistant prostate cancerRenal Cell Carcinoma
Inactive Indication-
Originator Organization
Regeneron Pharmaceuticals, Inc.Regeneron Pharmaceuticals, Inc.
Active Organization
Regeneron Pharmaceuticals, Inc.Regeneron Pharmaceuticals, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with REGN15505
NCT07594106
/ RecruitingPhase 1/2
Phase 1/2 Study of REGN15505 (a PSMAx4-1BB Bispecific Antibody) Administered Alone or in Combination With Cemiplimab or REGN4336 (a PSMAxCD3 Bispecific Antibody) in Patients With Metastatic Castration-Resistant Prostate Cancer and Clear Cell Renal Cell Carcinoma
100 Clinical Results associated with REGN15505
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100 Translational Medicine associated with REGN15505
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100 Patents (Medical) associated with REGN15505
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100 Deals associated with REGN15505
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic castration-resistant prostate cancerPhase 2
United States
Regeneron Pharmaceuticals, Inc.Regeneron Pharmaceuticals, Inc.
20 Jul 2026
Renal Cell CarcinomaPhase 2
United States
Regeneron Pharmaceuticals, Inc.Regeneron Pharmaceuticals, Inc.
20 Jul 2026
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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