Last update 30 Oct 2025

mGluR2/mGluR3 positive allosteric modulator 20(Emory University)

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
mGluR2 x mGluR3
Action
positive allosteric modulator
Mechanism
mGluR2 positive allosteric modulator(Metabotropic glutamate receptor 2 positive allosteric modulator), mGluR3 positive allosteric modulator(Metabotropic glutamate receptor 3 positive allosteric modulator)
Therapeutic Areas
Nervous System Diseases
Active Indication
Central Nervous System Diseases
Inactive Indication-
Originator Organization
Emory UniversityEmory University
Active Organization
Emory UniversityEmory University
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC25H22ClNO5
InChIKeySRGMPUVJRINMDU-UHFFFAOYSA-N
CAS Registry3067362-81-3

Related

100 Clinical Results associated with mGluR2/mGluR3 positive allosteric modulator 20(Emory University)
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100 Translational Medicine associated with mGluR2/mGluR3 positive allosteric modulator 20(Emory University)
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100 Patents (Medical) associated with mGluR2/mGluR3 positive allosteric modulator 20(Emory University)
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1
Literatures (Medical) associated with mGluR2/mGluR3 positive allosteric modulator 20(Emory University)
10 Jul 2025ACS Medicinal Chemistry Letters
Novel Isoindolin-1-one Derivatives as Metabotropic Glutamate Receptor Positive Allosteric Modulators
100 Deals associated with mGluR2/mGluR3 positive allosteric modulator 20(Emory University)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Central Nervous System DiseasesPreclinical
United States
Emory UniversityEmory University
18 Jun 2025
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Clinical Result

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Regulation

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