Last update 27 Sep 2025

GNR-038

Overview

Basic Info

Drug Type
Recombinant protein
Synonyms
GNR 038
Target
C1-INH
Action
modulators
Mechanism
C1-INH modulators(serpin family G member 1 modulators)
Therapeutic Areas
Immune System DiseasesCardiovascular DiseasesCongenital Disorders+ [2]
Active Indication-
Inactive Indication
Hereditary Angioedema
Originator Organization-
Active Organization-
Inactive Organization
Generium ZAOGenerium ZAO
License Organization-
Drug Highest PhaseDiscontinuedPhase 2/3
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with GNR-038
NCT04898309
/ WithdrawnPhase 2/3
A Placebo-controlled Randomized Trial to Evaluate the Efficacy and Safety of GNR-038 in Comparison With Berinert® for Acute Attacks Relief in Patients With Hereditary Angioedema
NCT04557319
/ CompletedPhase 1
An Open Study of the Safety and Pharmacokinetics of GNR-038 in Sequential Dose-increase Cohorts in Healthy Volunteers
100 Clinical Results associated with GNR-038
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100 Translational Medicine associated with GNR-038
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100 Patents (Medical) associated with GNR-038
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100 Deals associated with GNR-038
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hereditary AngioedemaPhase 3
Russia
Generium ZAOGenerium ZAO
01 Dec 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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