Last update 01 Nov 2024

Brinzolamide/Travoprost

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Travoprost/brinzolamide
Target
CA2 x PTGFR
Mechanism
CA2 inhibitors(Carbonic anhydrase II inhibitors), PTGFR agonists(Prostanoid FP receptor agonists)
Therapeutic Areas
Eye Diseases
Active Indication-
Inactive Indication
GlaucomaGlaucoma, Open-Angle
Originator Organization
Alcon AGAlcon AG
Active Organization-
Inactive Organization
Alcon Research Ltd.Alcon-Couvreur NV
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure

Molecular FormulaC26H35F3O6
InChIKeyMKPLKVHSHYCHOC-AHTXBMBWSA-N
CAS Registry157283-68-6
View All Structures (2)

Related

3
Clinical Trials associated with Brinzolamide/Travoprost
NCT00767494 / TerminatedPhase 3
Travoprost/Brinzolamide Fixed Combination Versus Travatan and Versus AZOPT
NCT00527501 / CompletedPhase 2
IOP Lowering Efficacy of Travoprost/Brinzolamide Fixed Combination Ophthalmic Suspension in Patients With Open-Angle Glaucoma or Ocular Hypertension
NCT00372827 / CompletedPhase 4
Efficacy and Safety of Timolol Maleate 0.5% Compared to Brinzolamide 1% When Added to Travoprost 0.004% in Primary Open-angle Glaucoma or Ocular Hypertension
100 Clinical Results associated with Brinzolamide/Travoprost
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100 Translational Medicine associated with Brinzolamide/Travoprost
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100 Patents (Medical) associated with Brinzolamide/Travoprost
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100 Deals associated with Brinzolamide/Travoprost
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Glaucoma, Open-AnglePhase 3
US
Alcon Research Ltd.
01 Aug 2007
GlaucomaPhase 2
BE
Alcon Research Ltd.
01 Oct 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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