Delving into the Latest Updates on Contezolid acefosamil(Akashi Therapeutics) with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms-

Target

PLA2

Mechanism

PLA2 inhibitors(Phospholipases A2 inhibitors)

Therapeutic Areas

Immune System DiseasesInfectious DiseasesOtorhinolaryngologic Diseases+ [1]

Active Indication-

Inactive Indication

Rhinitis, Allergic

Originator Organization

Akashi Therapeutics Inc

Active Organization-

Inactive Organization

Akashi Therapeutics Inc

Celsus Therapeutics Plc

Drug Highest PhasePendingPhase 2

First Approval Date-

Regulation-

Login to view timeline

A Phase 1 study of the safety, tolerability, and pharmacokinetics of a new oxazolidinone antibiotic. In Part 1 cohorts of healthy adults will participate in a single dose escalation study of increasing intravenous doses of MRX-4. In Part 2 cohorts of healthy adults will participate in a multiple dose escalation study of increasing intravenous doses of MRX-4 given twice daily for ten days. Part 3 is a crossover study of oral MRX-4 versus a comparable intravenous dose of MRX-4 to determine bioavailability.

Start Date01 Oct 2016

Sponsor / Collaborator

MicuRx Pharmaceuticals, Inc.

[+1]

NCT03033342 / CompletedPhase 1

Randomized, Double-Blind, Placebo-Controlled Three-Part Phase 1 Study of Safety, Tolerability, Pharmacokinetics, and Food Effect of MRX-4 Administered Orally to Healthy Volunteers in Single and Multiple Ascending Dose Cohorts to Evaluate Drug Interactions With Omeprazole

A phase one study of the safety, tolerability, and pharmacokinetics of a new oxazolidinone antibiotic. Cohorts of healthy adults (female and male) will participate in:
single dose escalation study of increasing doses of MRX-4 given by mouth others will participate in multiple dose escalation cohorts of MRX-4 given twice daily by mouth.
other cohorts of subjects will participate in the study to evaluate the impact of concomitant food or Omeprazole on safety, tolerability and pharmacokinetics of MRX-4

Start Date02 Aug 2016

Sponsor / Collaborator

MicuRx Pharmaceuticals, Inc.

[+1]

100 Clinical Results associated with Contezolid acefosamil(Akashi Therapeutics)

Login to view more data

100 Translational Medicine associated with Contezolid acefosamil(Akashi Therapeutics)

Login to view more data

100 Patents (Medical) associated with Contezolid acefosamil(Akashi Therapeutics)

Login to view more data

100 Deals associated with Contezolid acefosamil(Akashi Therapeutics)

Login to view more data