Last update 08 May 2025

Anti Claudin18.2 humanized monoclonal antibody(Hualan Genetic Engineering)

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms-
Target
CLDN18.2
Action
inhibitors
Mechanism
CLDN18.2 inhibitors(Claudin 18.2 inhibitors), ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects), Complement dependent cytotoxicity (CDC) effects
Therapeutic Areas
NeoplasmsDigestive System Disorders
Active Indication
CLDN18.2 positive Gastroesophageal junction adenocarcinoma
Inactive Indication-
Originator Organization
Hualan Genetic Engineering (Henan) Co.,Ltd
Active Organization
Hualan Genetic Engineering (Henan) Co.,Ltd
Inactive Organization-
License Organization-
Drug Highest PhaseIND Approval
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with Anti Claudin18.2 humanized monoclonal antibody(Hualan Genetic Engineering)
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100 Translational Medicine associated with Anti Claudin18.2 humanized monoclonal antibody(Hualan Genetic Engineering)
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100 Patents (Medical) associated with Anti Claudin18.2 humanized monoclonal antibody(Hualan Genetic Engineering)
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100 Deals associated with Anti Claudin18.2 humanized monoclonal antibody(Hualan Genetic Engineering)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
CLDN18.2 positive Gastroesophageal junction adenocarcinomaIND Approval
China
Hualan Genetic Engineering (Henan) Co.,Ltd
05 Dec 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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