Last update 30 Oct 2025

HER2-Auristatin analogs(Adcentrx)

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms-
Target
HER2 x Tubulin
Action
antagonists, inhibitors
Mechanism
HER2 antagonists(Receptor tyrosine-protein kinase erbB-2 antagonists), Tubulin inhibitors
Therapeutic Areas
Neoplasms
Active Indication
Neoplasms
Inactive Indication-
Originator Organization
Adcentrx Therapeutics, Inc.Adcentrx Therapeutics, Inc.
Active Organization
Adcentrx Therapeutics, Inc.Adcentrx Therapeutics, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC39H62N6O5S
InChIKeyVNKVPXRCRUDPAH-JYZGKHMWSA-N
CAS Registry-
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Related

100 Clinical Results associated with HER2-Auristatin analogs(Adcentrx)
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100 Translational Medicine associated with HER2-Auristatin analogs(Adcentrx)
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100 Patents (Medical) associated with HER2-Auristatin analogs(Adcentrx)
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100 Deals associated with HER2-Auristatin analogs(Adcentrx)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
United States
Adcentrx Therapeutics, Inc.Adcentrx Therapeutics, Inc.
17 Apr 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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