Last update 01 Nov 2025

SPESN38-5

Overview

Basic Info

Drug Type
Chemical drugs
Synonyms
SPESN38-5
Target
Top I
Action
inhibitors
Mechanism
TOP1 inhibitors(DNA topoisomerase I inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersOther Diseases
Active Indication
NeoplasmsColorectal CancerSoft Tissue Sarcoma
Inactive Indication-
Originator Organization
Sunstate Biosciences LLC
Active Organization
Sunstate Biosciences LLCCalifornia Institute of TechnologyCalifornia Institute of TechnologyThe UC Irvine Medical Center
+ [1]
Inactive Organization-
License Organization-
Drug Highest PhaseIND Application
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with SPESN38-5
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100 Translational Medicine associated with SPESN38-5
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100 Patents (Medical) associated with SPESN38-5
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100 Deals associated with SPESN38-5
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsIND Application
United States
The UC Irvine Medical Center
17 Nov 2022
NeoplasmsIND Application
United States
Sunstate Biosciences LLC
17 Nov 2022
NeoplasmsIND Application
United States
Cedars-Sinai Health System
17 Nov 2022
Colorectal CancerPreclinical
United States
Sunstate Biosciences LLC
10 Dec 2023
Colorectal CancerPreclinical
United States
California Institute of TechnologyCalifornia Institute of Technology
10 Dec 2023
Soft Tissue SarcomaPreclinical
United States
Sunstate Biosciences LLC
10 Dec 2023
Soft Tissue SarcomaPreclinical
United States
California Institute of TechnologyCalifornia Institute of Technology
10 Dec 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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