Last update 17 Jul 2026

GFS202A

Overview

Basic Info

Drug Type
Bispecific antibody
Synonyms
GFS-202A
Target
GDF15 x IL-6
Action
inhibitors
Mechanism
GDF15 inhibitors(Growth/differentiation factor 15 inhibitors), IL-6 inhibitors(Interleukin-6 inhibitors)
Therapeutic Areas
Other DiseasesNeoplasms
Active Indication
CachexiaKRAS G12D mutation Solid Tumors
Inactive Indication-
Originator Organization
Genfleet Therapeutics (Shanghai), Inc.Genfleet Therapeutics (Shanghai), Inc.
Active Organization
Genfleet Therapeutics (Shanghai), Inc.Genfleet Therapeutics (Shanghai), Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with GFS202A
NCT06898255
/ RecruitingPhase 1
An Open-label, Multi-center, Phase I Study to Evaluate the Safety/Tolerability and Pharmacokinetics of GFS202A in Advanced Solid Tumor Patients With Pre-cachexia or Cachexia
100 Clinical Results associated with GFS202A
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100 Translational Medicine associated with GFS202A
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100 Patents (Medical) associated with GFS202A
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100 Deals associated with GFS202A
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
CachexiaPhase 1
China
Genfleet Therapeutics (Shanghai), Inc.Genfleet Therapeutics (Shanghai), Inc.
16 Apr 2025
KRAS G12D mutation Solid TumorsIND Approval
China
Genfleet Therapeutics (Shanghai), Inc.Genfleet Therapeutics (Shanghai), Inc.
15 Jul 2026
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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