Delving into the Latest Updates on Autologous Cultured Adipose-Derived Stem Cells(Anterogen) with Synapse

Overview

Basic Info

Drug Type

Stem cell therapy

Synonyms-

Target-

Action-

Mechanism

Stem cell replacements

Therapeutic Areas

Other DiseasesDigestive System Disorders

Active Indication-

Inactive Indication

Fecal IncontinencePerianal fistula

Originator Organization

Anterogen Co., Ltd.

Active Organization-

Inactive Organization

Anterogen Co., Ltd.

License Organization-

Drug Highest PhaseDiscontinuedPhase 2

First Approval Date-

Regulation-

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Mesenchymal stem cells derived from adipose tissue are pluripotent to differentiate into myocytes, adipocytes or others. They have an immunosuppressive activity. Complex perianal fistula is difficult to cure and easy to relapse. Autologous adipose stem cells have shown efficacy and safety on Crohn's fistula in phase 1 study. Based on these results, the investigators would apply autologous adipose stem cells on complex perianal fistula to evaluate their efficacy and safety.

Start Date01 Jan 2011

Sponsor / Collaborator

Anterogen Co., Ltd.

NCT01623453

/ TerminatedNot Applicable

A Follow-up Study to Evaluate the Sustained Healing Effect the Patients Who Showed Complete Closure of Fistula the Previous ANTG-ASC-210 Study

This is an open follow-up clinical trial to evaluate a sustained efficacy and safety of ANTG-ASC injection for 4 months (6 months after final dose injection) after Phase II clinical trial.

Start Date01 Sep 2010

Sponsor / Collaborator

Anterogen Co., Ltd.

NCT01011686

/ TerminatedPhase 1

A Phase I Clinical Study of ANT-SM (Autologous Cultured Adipose-derived Stem Cell) for the Treatment of Fecal Incontinence to Evaluate Safety

Fecal incontinence affects 18.4% adults in the community and greatly impacts quality of life. There's a problem like inconvenience, pain or allergic response in many therapeutic methods such as a surgical operation or material injection. ANT-SM is autologous adipose-derived stem cell, and so, expect of no immune responses. In this study, patients are given injection of ANT-AM in anal sphincter and followed for 4 weeks to test the safety.

Start Date-

Sponsor / Collaborator

Anterogen Co., Ltd.

100 Clinical Results associated with Autologous Cultured Adipose-Derived Stem Cells(Anterogen)

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100 Translational Medicine associated with Autologous Cultured Adipose-Derived Stem Cells(Anterogen)

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100 Patents (Medical) associated with Autologous Cultured Adipose-Derived Stem Cells(Anterogen)

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100 Deals associated with Autologous Cultured Adipose-Derived Stem Cells(Anterogen)

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