Last update 06 Dec 2025

COVA4231

Overview

Basic Info

Drug Type
Bispecific T-cell Engager (BiTE)
Synonyms
COVA4231
Target
CD3 x CD33
Action
stimulants, inhibitors
Mechanism
CD3 stimulants(T cell surface glycoprotein CD3 stimulants), CD33 inhibitors(Myeloid cell surface antigen CD33 inhibitors)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication-
Inactive Indication
Acute Myeloid Leukemia
Originator Organization
Covagen AGCovagen AG
Active Organization-
Inactive Organization
Covagen AGCovagen AG
License Organization-
Drug Highest PhaseDiscontinuedPreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with COVA4231
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100 Translational Medicine associated with COVA4231
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100 Patents (Medical) associated with COVA4231
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1
Literatures (Medical) associated with COVA4231
01 Mar 2019LeukemiaQ1 · MEDICINE
COVA4231, a potent CD3/CD33 bispecific FynomAb with IgG-like pharmacokinetics for the treatment of acute myeloid leukemia
Q1 · MEDICINE
100 Deals associated with COVA4231
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPreclinical-
Covagen AGCovagen AG
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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