Last update 10 Jan 2026

CG1xCD3xCD28 T cell engager(Crossbow Therapeutics)

Overview

Basic Info

Drug Type
Trispecific T-cell engager (TriTE)
Synonyms-
Target
CD28 x CD3 x MAMLD1
Action
agonists, stimulants, modulators
Mechanism
CD28 agonists(T-cell-specific surface glycoprotein CD28 agonists), CD3 stimulants(T cell surface glycoprotein CD3 stimulants), MAMLD1 modulators(mastermind like domain containing 1 modulators)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Leukemia
Inactive Indication-
Originator Organization
Crossbow Therapeutics, Inc.Crossbow Therapeutics, Inc.
Active Organization
Crossbow Therapeutics, Inc.Crossbow Therapeutics, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with CG1xCD3xCD28 T cell engager(Crossbow Therapeutics)
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100 Translational Medicine associated with CG1xCD3xCD28 T cell engager(Crossbow Therapeutics)
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100 Patents (Medical) associated with CG1xCD3xCD28 T cell engager(Crossbow Therapeutics)
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100 Deals associated with CG1xCD3xCD28 T cell engager(Crossbow Therapeutics)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
LeukemiaPreclinical
United States
Crossbow Therapeutics, Inc.Crossbow Therapeutics, Inc.
05 Nov 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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