Last update 24 Nov 2025

EKZ-438

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
HDAC6
Action
inhibitors
Mechanism
HDAC6 inhibitors(Histone deacetylase 6 inhibitors), Epigenetic drug
Therapeutic Areas
Nervous System DiseasesEndocrinology and Metabolic DiseaseOther Diseases
Active Indication
Amyotrophic Lateral SclerosisFrontotemporal Dementia
Inactive Indication-
Originator Organization
Eikonizo Therapeutics, Inc.Eikonizo Therapeutics, Inc.
Active Organization
Eikonizo Therapeutics, Inc.Eikonizo Therapeutics, Inc.
Esya, Inc.Esya, Inc.
PharmaDirections, Inc.PharmaDirections, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with EKZ-438
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100 Translational Medicine associated with EKZ-438
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100 Patents (Medical) associated with EKZ-438
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100 Deals associated with EKZ-438
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Amyotrophic Lateral SclerosisPreclinical
United States
Eikonizo Therapeutics, Inc.Eikonizo Therapeutics, Inc.
08 Oct 2025
Amyotrophic Lateral SclerosisPreclinical
United States
PharmaDirections, Inc.PharmaDirections, Inc.
08 Oct 2025
Amyotrophic Lateral SclerosisPreclinical
United Kingdom
Esya, Inc.Esya, Inc.
08 Oct 2025
Frontotemporal DementiaPreclinical
United States
PharmaDirections, Inc.PharmaDirections, Inc.
08 Oct 2025
Frontotemporal DementiaPreclinical
United States
Eikonizo Therapeutics, Inc.Eikonizo Therapeutics, Inc.
08 Oct 2025
Frontotemporal DementiaPreclinical
United Kingdom
Esya, Inc.Esya, Inc.
08 Oct 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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