Last update 15 Aug 2026

RO-6807952

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
MAR 701, MAR-701, RG 7685
+ [3]
Target
GIPR x GLP-1R
Action
agonists
Mechanism
GIPR agonists(Gastric inhibitory polypeptide receptor agonists), GLP-1R agonists(Glucagon-like peptide 1 receptor agonists)
Therapeutic Areas
Endocrinology and Metabolic Disease
Active Indication-
Inactive Indication
Diabetes Mellitus, Type 2
Originator Organization
Marcadia Biotech, Inc.Marcadia Biotech, Inc.
Active Organization-
Inactive Organization
Hoffmann-La Roche, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with RO-6807952
NCT01516476
/ TerminatedPhase 2
A Multi-Center, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy and Safety of RO6807952 in Type 2 Diabetic Patients Inadequately Controlled With Metformin Alone
NCT01358929
/ CompletedPhase 1
A Randomized, Placebo-Controlled, Sequential, Multiple-Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MAR701/RO6807952 in Type 2 Diabetic Patients
100 Clinical Results associated with RO-6807952
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100 Translational Medicine associated with RO-6807952
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100 Patents (Medical) associated with RO-6807952
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100 Deals associated with RO-6807952
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 2
United States
Hoffmann-La Roche, Inc.
01 Nov 2011
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Clinical Result

Indication
Phase
Evaluation
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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