Last update 20 Mar 2025

Oncolytic vaccinia virus (Hangzhou Gongchu Biotechnology)

Overview

Basic Info

Drug Type
Oncolytic virus
Synonyms
GC001溶瘤痘苗病毒
+ [1]
Target
STRIP1
Action
inhibitors
Mechanism
STRIP1 inhibitors(striatin interacting protein 1 inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease+ [4]
Active Indication
High grade gliomaAdvanced Malignant Solid NeoplasmBreast Cancer+ [8]
Inactive Indication-
Originator Organization
Hangzhou Gongchu Biotechnology Co., Ltd.
Active Organization
Hangzhou Gongchu Biotechnology Co., Ltd.
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

4
Clinical Trials associated with Oncolytic vaccinia virus (Hangzhou Gongchu Biotechnology)
NCT06660056
/ RecruitingPhase 1
A Phase I Study Evaluating the Safety, Tolerability, Biodistribution and Shedding of Oncolytic Vaccinia Virus GC001, Pharmacodynamics, Immunogenicity, and Antitumor Activity of the Virus in Patient With Recurrent or Progressive Gliomas
CTR20231135
/ RecruitingPhase 1
一项评估 GC001 溶瘤痘苗病毒注射液在晚期实体瘤患者中的安全性、耐受性、病毒的生物分布和脱落、药效学、免疫原性和抗肿瘤活性的 I 期临床研究
[Translation] A Phase I study evaluating the safety, tolerability, viral biodistribution and shedding, pharmacodynamics, immunogenicity, and antitumor activity of GC001 oncolytic vaccinia virus injection in patients with advanced solid tumors
NCT06508307
/ RecruitingPhase 1
A Phase I Study Evaluating the Safety, Tolerability, Biodistribution and Shedding of the Virus, Pharmacodynamics, Immunogenicity, and Antitumor Activity of GC001 Oncolytic Vaccinia Virus Injection in Patient With Advanced Solid Tumors.
100 Clinical Results associated with Oncolytic vaccinia virus (Hangzhou Gongchu Biotechnology)
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100 Translational Medicine associated with Oncolytic vaccinia virus (Hangzhou Gongchu Biotechnology)
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100 Patents (Medical) associated with Oncolytic vaccinia virus (Hangzhou Gongchu Biotechnology)
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100 Deals associated with Oncolytic vaccinia virus (Hangzhou Gongchu Biotechnology)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
China
Hangzhou Gongchu Biotechnology Co., Ltd.
26 Apr 2023
Breast CancerPhase 1
China
Hangzhou Gongchu Biotechnology Co., Ltd.
26 Apr 2023
Colonic CancerPhase 1
China
Hangzhou Gongchu Biotechnology Co., Ltd.
26 Apr 2023
Hepatocellular CarcinomaPhase 1
China
Hangzhou Gongchu Biotechnology Co., Ltd.
26 Apr 2023
Lung CancerPhase 1
China
Hangzhou Gongchu Biotechnology Co., Ltd.
26 Apr 2023
Ovarian CancerPhase 1
China
Hangzhou Gongchu Biotechnology Co., Ltd.
26 Apr 2023
Pancreatic CancerPhase 1
China
Hangzhou Gongchu Biotechnology Co., Ltd.
26 Apr 2023
SarcomaPhase 1
China
Hangzhou Gongchu Biotechnology Co., Ltd.
26 Apr 2023
Stomach CancerPhase 1
China
Hangzhou Gongchu Biotechnology Co., Ltd.
26 Apr 2023
Uterine Cervical CancerPhase 1
China
Hangzhou Gongchu Biotechnology Co., Ltd.
26 Apr 2023
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Clinical Result

Indication
Phase
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Approval

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Regulation

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