Last update 28 Mar 2026

WRN inhibitors-123(Merck Sharp & Dohme LLC)

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
WRN
Action
inhibitors
Mechanism
WRN inhibitors(WRN RecQ like helicase inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Neoplasms
Inactive Indication-
Originator Organization
Merck Sharp & Dohme LLCMSD Pharmaceuticals Pvt Ltd.
Active Organization
Merck Sharp & Dohme LLCMSD Pharmaceuticals Pvt Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC35H34ClF3N8O5
InChIKeyNCUZLKSDWLCIJF-UHFFFAOYSA-N
CAS Registry3069346-05-7

Related

100 Clinical Results associated with WRN inhibitors-123(Merck Sharp & Dohme LLC)
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100 Translational Medicine associated with WRN inhibitors-123(Merck Sharp & Dohme LLC)
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100 Patents (Medical) associated with WRN inhibitors-123(Merck Sharp & Dohme LLC)
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1
Literatures (Medical) associated with WRN inhibitors-123(Merck Sharp & Dohme LLC)
08 May 2025ACS Medicinal Chemistry Letters
Novel Spirocyclic WRN Helicase Inhibitors for Treating Cancer
100 Deals associated with WRN inhibitors-123(Merck Sharp & Dohme LLC)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
United States
Merck Sharp & Dohme LLC
25 Apr 2025
NeoplasmsPreclinical
India
MSD Pharmaceuticals Pvt Ltd.
25 Apr 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Clinical Trial

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Approval

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Regulation

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