[Translation] A Phase Ib/IIa clinical trial to evaluate the safety, tolerability, pharmacokinetic characteristics and antiviral efficacy of TQA3038 injection in patients with chronic hepatitis B
Ib期临床试验:
主要目的:
评价TQA3038注射液联合/不联合核苷酸类药物在初治/经治慢乙肝患者中的安全性和耐受性
次要目的:
评价TQA3038注射液联合/不联合核苷酸类药物在初治/经治慢乙肝患者中的抗病毒疗效
评价TQA3038注射液在初治/经治慢乙肝患者中的药代动力学(PK)特征
评价TQA3038注射液的免疫原性 IIa期临床试验:
主要目的:
评价TQA3038注射液联合核苷酸类药物在经治慢乙肝患者中的抗病毒疗效
次要目的:
评价TQA3038注射液联合核苷酸类药物在经治慢乙肝患者中的安全性和耐受性
[Translation] Phase Ib clinical trial:
Main purpose:
To evaluate the safety and tolerability of TQA3038 injection combined with/without nucleotide drugs in patients with chronic hepatitis B who have been treated for the first time/after treatment
Secondary purpose:
To evaluate the antiviral efficacy of TQA3038 injection combined with/without nucleotide drugs in patients with chronic hepatitis B who have been treated for the first time/after treatment
To evaluate the pharmacokinetic (PK) characteristics of TQA3038 injection in patients with chronic hepatitis B who have been treated for the first time/after treatment
To evaluate the immunogenicity of TQA3038 injection Phase IIa clinical trial:
Main purpose:
To evaluate the antiviral efficacy of TQA3038 injection combined with nucleotide drugs in patients with chronic hepatitis B who have been treated for the second time:
To evaluate the safety and tolerability of TQA3038 injection combined with nucleotide drugs in patients with chronic hepatitis B who have been treated for the second time