Last update 07 Jun 2025

DXC-018

Overview

Basic Info

Drug Type
Dual payload Antibody drug conjugate (Dual payload ADC)
Synonyms
DXC 018, DXC-018, DXC018
Target
HER2 x Top I
Action
antagonists, inhibitors
Mechanism
HER2 antagonists(Receptor tyrosine-protein kinase erbB-2 antagonists), TOP1 inhibitors(DNA topoisomerase I inhibitors)
Therapeutic Areas
NeoplasmsDigestive System Disorders
Active Indication
Gastrointestinal Neoplasms
Inactive Indication-
Originator Organization
Hangzhou DAC Biotechnology Co., Ltd.Hangzhou DAC Biotechnology Co., Ltd.
Active Organization
Hangzhou DAC Biotechnology Co., Ltd.Hangzhou DAC Biotechnology Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhaseIND Application
First Approval Date-
Regulation-
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Structure/Sequence

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Related

100 Clinical Results associated with DXC-018
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100 Translational Medicine associated with DXC-018
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100 Patents (Medical) associated with DXC-018
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100 Deals associated with DXC-018
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Gastrointestinal NeoplasmsPreclinical
China
Hangzhou DAC Biotechnology Co., Ltd.Hangzhou DAC Biotechnology Co., Ltd.
28 Apr 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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