Delving into the Latest Updates on SYN045 with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

Target-

Mechanism-

Therapeutic Areas-

Active Indication

Pulmonary Arterial Hypertension

Inactive Indication-

Originator Organization

Shijiazhuang No. 4 Pharmaceutical Co., Ltd.

Active Organization

Shijiazhuang No. 4 Pharmaceutical Co., Ltd.

Inactive Organization-

Drug Highest PhasePhase 1

First Approval Date-

Regulation-

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主要目的：评价SYN045片在健康受试者中单次口服给药和不同饮食条件下给药的安全性和耐受性。次要目的：评价SYN045片在健康受试者中单次口服给药和不同饮食条件下给药后的药代动力学特征。探索性目的：探索SYN045在血浆、尿液和粪便中的代谢物谱。

[Translation]

Primary objective: To evaluate the safety and tolerability of SYN045 tablets after single oral administration and administration under different dietary conditions in healthy subjects. Secondary objective: To evaluate the pharmacokinetic characteristics of SYN045 tablets after single oral administration and administration under different dietary conditions in healthy subjects. Exploratory objective: To explore the metabolite profiles of SYN045 in plasma, urine and feces.

Start Date07 May 2024

Sponsor / Collaborator

Shijiazhuang No. 4 Pharmaceutical Co., Ltd.

ChiCTR2400083835 / RecruitingPhase 1IIT

Phase I clinical study to investigate the safety, tolerability, pharmacokinetic of single doses of SYN045 tablets in healthy subjects and the effect of food on pharmacokinetics

Start Date06 May 2024

Sponsor / Collaborator

Anhui Medical University No. 1 Affiliated Hospital

100 Clinical Results associated with SYN045

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100 Translational Medicine associated with SYN045

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100 Patents (Medical) associated with SYN045

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100 Deals associated with SYN045

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