Last update 08 May 2025

Naltrexone/ondansetron/topiramate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
AMPA receptor x CAs x GABAA receptor x HTR3 x Kainic acid receptor x Opioid receptors x Sodium channels
Action
agonists, antagonists, inhibitors,
+ [1]
Mechanism
5-HT3 receptor agonists(5-hydroxytryptamine receptors, ionotropic (HTR3) agonists), AMPA receptor antagonists(Glutamate receptor ionotropic AMPA antagonists), CAs inhibitors(Carbonic anhydrases inhibitors)
+ [4]
Therapeutic Areas
Other Diseases
Active Indication-
Inactive Indication
Alcoholism
Originator Organization
Adial Pharmaceuticals, Inc.Adial Pharmaceuticals, Inc.
Active Organization-
Inactive Organization
Adial Pharmaceuticals, Inc.Adial Pharmaceuticals, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC12H21NO8S
InChIKeyKJADKKWYZYXHBB-XBWDGYHZSA-N
CAS Registry97240-79-4
View All Structures (3)

Related

100 Clinical Results associated with Naltrexone/ondansetron/topiramate
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100 Translational Medicine associated with Naltrexone/ondansetron/topiramate
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100 Patents (Medical) associated with Naltrexone/ondansetron/topiramate
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100 Deals associated with Naltrexone/ondansetron/topiramate
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AlcoholismPreclinical
United States
Adial Pharmaceuticals, Inc.Adial Pharmaceuticals, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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