[Translation] A Phase I Clinical Trial to Study the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Subcutaneous Injection of SHR-3167 Injection in Healthy Subjects and Patients with Type 2 Diabetes
主要研究目的:
1.评价健康受试者和2 型糖尿病(T2DM)患者单次皮下注射SHR-3167 注射液的安全性和耐受性。
次要研究目的:
1.评价健康受试者和T2DM 患者单次皮下注射SHR-3167 注射液的药代动力学特征。
2.评价健康受试者和T2DM 患者单次皮下注射SHR-3167 注射液的免疫原性特征。
3.评价健康受试者和T2DM 患者单次皮下注射SHR-3167 注射液的药效学特征。
[Translation] Main study objectives:
1. To evaluate the safety and tolerability of a single subcutaneous injection of SHR-3167 injection in healthy subjects and patients with type 2 diabetes (T2DM).
Secondary study objectives:
1. To evaluate the pharmacokinetic characteristics of a single subcutaneous injection of SHR-3167 injection in healthy subjects and patients with T2DM.
2. To evaluate the immunogenicity characteristics of a single subcutaneous injection of SHR-3167 injection in healthy subjects and patients with T2DM.
3. To evaluate the pharmacodynamic characteristics of a single subcutaneous injection of SHR-3167 injection in healthy subjects and patients with T2DM.