Last update 21 Nov 2024

LX-1033

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
TPH1 x TPH2
Mechanism
TPH1 inhibitors(Tryptophan hydroxylase 1 inhibitors), TPH2 inhibitors(Tryptophan hydroxylase 2 inhibitors)
Therapeutic Areas
Digestive System Disorders
Active Indication-
Inactive Indication
Irritable bowel syndrome with diarrhea
Originator Organization
Lexicon Pharmaceuticals, Inc.Lexicon Pharmaceuticals, Inc.
Active Organization-
Inactive Organization
Lexicon Pharmaceuticals, Inc.Lexicon Pharmaceuticals, Inc.
Drug Highest PhasePendingPhase 2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with LX-1033
NCT01494233 / CompletedPhase 2
A Phase 2, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Multiple-Dose Study to Determine the Safety and Efficacy of Orally Administered LX1033 in Subjects With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)
100 Clinical Results associated with LX-1033
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100 Translational Medicine associated with LX-1033
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100 Patents (Medical) associated with LX-1033
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100 Deals associated with LX-1033
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Irritable bowel syndrome with diarrheaPhase 2
US
Lexicon Pharmaceuticals, Inc.Lexicon Pharmaceuticals, Inc.
01 Feb 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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