Last update 08 May 2025

EGFRt/BCMA-41BBz CAR T cell(Juno Therapeutics,)

Overview

Basic Info

Drug Type
CAR-T
Synonyms-
Target
4-1BB x BCMA x EGFR
Action
modulators
Mechanism
4-1BB modulators(Tumor necrosis factor receptor superfamily member 9 modulators), BCMA modulators(B-cell maturation protein modulators), EGFR modulators(Epidermal growth factor receptor erbB1 modulators)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication
Multiple Myeloma
Inactive Indication-
Originator Organization
Juno Therapeutics, Inc.Juno Therapeutics, Inc.
Active Organization
Juno Therapeutics, Inc.Juno Therapeutics, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with EGFRt/BCMA-41BBz CAR T cell(Juno Therapeutics,)
NCT03070327
/ Active, not recruitingPhase 1IIT
A Phase I Trial of B-cell Maturation Antigen (BCMA) Targeted EGFRt/BCMA-41BBz Chimeric Antigen Receptor (CAR) Modified T Cells With or Without Lenalidomide for the Treatment of Multiple Myeloma (MM)
100 Clinical Results associated with EGFRt/BCMA-41BBz CAR T cell(Juno Therapeutics,)
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100 Translational Medicine associated with EGFRt/BCMA-41BBz CAR T cell(Juno Therapeutics,)
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100 Patents (Medical) associated with EGFRt/BCMA-41BBz CAR T cell(Juno Therapeutics,)
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100 Deals associated with EGFRt/BCMA-41BBz CAR T cell(Juno Therapeutics,)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Multiple MyelomaPhase 1
United States
Juno Therapeutics, Inc.Juno Therapeutics, Inc.
27 Feb 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Clinical Trial

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Approval

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Regulation

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