Last update 05 Apr 2025

VBC108

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms-
Target
CDH17 x CLDN18.2 x Top I
Action
antagonists, inhibitors
Mechanism
CDH17 antagonists(Cadherin-17 antagonists), CLDN18.2 inhibitors(Claudin 18.2 inhibitors), TOP1 inhibitors(DNA topoisomerase I inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease
Active Indication
Colorectal CancerPancreatic Ductal AdenocarcinomaStomach Cancer
Inactive Indication-
Originator Organization
Shanghai VelaVigo Co. Ltd.Shanghai VelaVigo Co. Ltd.
Active Organization
VelaVigo (Hong Kong) LimitedShanghai VelaVigo Co. Ltd.Shanghai VelaVigo Co. Ltd.
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

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Related

100 Clinical Results associated with VBC108
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100 Translational Medicine associated with VBC108
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100 Patents (Medical) associated with VBC108
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100 Deals associated with VBC108
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Colorectal CancerPreclinical
China
Shanghai VelaVigo Co. Ltd.Shanghai VelaVigo Co. Ltd.
27 Apr 2025
Colorectal CancerPreclinical
Hong Kong
VelaVigo (Hong Kong) Limited
27 Apr 2025
Pancreatic Ductal AdenocarcinomaPreclinical
China
Shanghai VelaVigo Co. Ltd.Shanghai VelaVigo Co. Ltd.
27 Apr 2025
Pancreatic Ductal AdenocarcinomaPreclinical
Hong Kong
VelaVigo (Hong Kong) Limited
27 Apr 2025
Stomach CancerPreclinical
China
Shanghai VelaVigo Co. Ltd.Shanghai VelaVigo Co. Ltd.
27 Apr 2025
Stomach CancerPreclinical
Hong Kong
VelaVigo (Hong Kong) Limited
27 Apr 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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