Last update 23 Jul 2025

TVB-3166

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
FASN
Action
inhibitors
Mechanism
FAS inhibitors(Fatty acid synthase inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Neoplasms
Inactive Indication-
Originator Organization
Sagimet Biosciences, Inc.Sagimet Biosciences, Inc.
Active Organization
Sagimet Biosciences, Inc.Sagimet Biosciences, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC24H24N4O
InChIKeyICDQFUFDAFKCAX-UHFFFAOYSA-N
CAS Registry1533438-83-3

Related

100 Clinical Results associated with TVB-3166
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100 Translational Medicine associated with TVB-3166
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100 Patents (Medical) associated with TVB-3166
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28
Literatures (Medical) associated with TVB-3166
01 Apr 2025NEOPLASIA
Fatty acid synthase (FASN) inhibition cooperates with BH3 mimetic drugs to overcome resistance to mitochondrial apoptosis in pancreatic cancer
01 Nov 2024ORAL DISEASES
Isolation and phenotypic characterization of cancer stem cells from metastatic oral cancer cells
28 Feb 2024Science translational medicineQ1 · MEDICINE
Acetyl-CoA carboxylase 1 controls a lipid droplet–peroxisome axis and is a vulnerability of endocrine-resistant ER + breast cancer
Q1 · MEDICINE
100 Deals associated with TVB-3166
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
United States
Sagimet Biosciences, Inc.Sagimet Biosciences, Inc.
01 Aug 2015
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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