Last update 29 Aug 2026

PHA665752-based degraders 9(Dana-Farber Cancer Institute)

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms-
Target
c-Met
Action
degraders
Mechanism
c-Met degraders(Hepatocyte growth factor receptor degraders)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication-
Inactive Indication
Leukemia
Originator Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.
Active Organization-
Inactive Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC44H44Cl2N6O8S
InChIKeyLQEMUVVPBROAPO-SWKFRHMKSA-N
CAS Registry2222635-86-9

Related

100 Clinical Results associated with PHA665752-based degraders 9(Dana-Farber Cancer Institute)
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100 Translational Medicine associated with PHA665752-based degraders 9(Dana-Farber Cancer Institute)
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100 Patents (Medical) associated with PHA665752-based degraders 9(Dana-Farber Cancer Institute)
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100 Deals associated with PHA665752-based degraders 9(Dana-Farber Cancer Institute)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
LeukemiaPreclinical
United States
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
22 Jan 2018
LeukemiaPreclinical
United States
Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.
22 Jan 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Approval

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Regulation

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