Last update 24 May 2025

AccuADC-001

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC), Biosimilar
Synonyms
恩美曲妥珠单抗生物类似药（Defence）, ACCUADC 001, ACCUADC-001
+ [1]
Target
HER2 x Tubulin
Action
antagonists, inhibitors
Mechanism
HER2 antagonists(Receptor tyrosine-protein kinase erbB-2 antagonists), Tubulin inhibitors, ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects)
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication
Breast Cancer
Inactive Indication
Stomach Cancer
Originator Organization
Defence Therapeutics IncDefence Therapeutics Inc
Active Organization
Defence Therapeutics IncDefence Therapeutics Inc
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC35H48ClN3O10S
InChIKeyANZJBCHSOXCCRQ-FKUXLPTCSA-N
CAS Registry139504-50-0
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Related

100 Clinical Results associated with AccuADC-001
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100 Translational Medicine associated with AccuADC-001
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100 Patents (Medical) associated with AccuADC-001
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100 Deals associated with AccuADC-001
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Stomach CancerPreclinical
Canada
Defence Therapeutics IncDefence Therapeutics Inc
01 Dec 2021
Breast CancerPreclinical-
Defence Therapeutics IncDefence Therapeutics Inc
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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