Last update 24 May 2025

PHI-501

Overview

Basic Info

Drug Type
Biological products
Synonyms
PHI-501
Target
DDR1 x NRAS x Raf kinase
Action
antagonists, inhibitors
Mechanism
DDR1 antagonists(Discoidin domain receptor 1 antagonists), NRAS inhibitors(GTPase NRas inhibitors), Raf kinase inhibitors(RAF serine/threonine protein kinase inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersSkin and Musculoskeletal Diseases+ [1]
Active Indication
Colonic CancerMelanomaTriple Negative Breast Cancer+ [1]
Inactive Indication
Acute Myeloid Leukemia
Originator Organization
Pharos iBio Co., Ltd.Pharos iBio Co., Ltd.
Active Organization
Pharos iBio Co., Ltd.Pharos iBio Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhaseIND Application
First Approval Date-
RegulationOrphan Drug (United States)
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Related

100 Clinical Results associated with PHI-501
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100 Translational Medicine associated with PHI-501
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100 Patents (Medical) associated with PHI-501
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100 Deals associated with PHI-501
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Colonic CancerIND Application
South Korea
Pharos iBio Co., Ltd.Pharos iBio Co., Ltd.
30 Jul 2024
MelanomaIND Application
South Korea
Pharos iBio Co., Ltd.Pharos iBio Co., Ltd.
30 Jul 2024
Triple Negative Breast CancerIND Application
South Korea
Pharos iBio Co., Ltd.Pharos iBio Co., Ltd.
30 Jul 2024
Lung CancerPreclinical
South Korea
Pharos iBio Co., Ltd.Pharos iBio Co., Ltd.
29 Apr 2025
Acute Myeloid LeukemiaPreclinical
South Korea
Pharos iBio Co., Ltd.Pharos iBio Co., Ltd.
03 Dec 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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