Delving into the Latest Updates on SHR-2002 with Synapse

Overview

Basic Info

Drug Type

Bispecific antibody

Synonyms

Target

Mechanism

CD112R antagonists(Transmembrane protein PVRIG antagonists), TIGIT inhibitors(T cell immunoglobulin and ITIM domains inhibitors)

Therapeutic Areas

Neoplasms

Active Indication

Advanced cancerNeoplasmsSolid tumor

Inactive Indication-

Originator Organization

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Active Organization

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Shanghai Hengrui Pharmaceutical Co., Ltd.Atridia Pty Ltd.

Inactive Organization-

Drug Highest PhasePhase 1

First Approval Date-

Regulation-

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To evaluate the safety and tolerability of SHR-2002 alone or in combination with SHR-1316 in patients with advanced malignant tumors, and to determine the maximum tolerated dose (MTD) or maximum administered dose (MAD) and the recommended dose (RP2D) for Phase II clinical studies of SHR-2002 combined with SHR-1316.

Start Date22 Feb 2022

Sponsor / Collaborator

Shanghai Hengrui Pharmaceutical Co., Ltd.

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NCT05082545 / CompletedPhase 1

A Phase I Clinical Study on the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of SHR-2002 Injection in Combination With SHR-1316 in Patients With Advanced Malignant Tumors

This is Phase 1 study FIH to check "Dose Escalation, Dose expansion and Indication expansion". This study is AUSTRALIA only study.

Start Date23 Nov 2021

Sponsor / Collaborator

Atridia Pty Ltd.

100 Clinical Results associated with SHR-2002

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100 Translational Medicine associated with SHR-2002

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100 Patents (Medical) associated with SHR-2002

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100 Deals associated with SHR-2002

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R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Advanced cancer	Phase 1	CN	Shanghai Hengrui Pharmaceutical Co., Ltd.	22 Feb 2022
Advanced cancer	Phase 1	CN	Suzhou Suncadia Biopharmaceuticals Co., Ltd.	22 Feb 2022
Neoplasms	Phase 1	AU	Atridia Pty Ltd.	23 Nov 2021
Solid tumor	IND Approval	CN	Suzhou Suncadia Biopharmaceuticals Co., Ltd.	15 Dec 2023