Last update 28 Mar 2026

AVI-5126

Overview

Basic Info

Drug Type
ASO
Synonyms
Restin-CP, AVI 5126, GTX 5126
Target
c-Myc
Action
inhibitors
Mechanism
MYC gene inhibitors
Therapeutic Areas
Cardiovascular DiseasesOther Diseases
Active Indication-
Inactive Indication
Coronary Artery DiseaseCoronary RestenosisGraft dysfunction
Originator Organization
Sarepta Therapeutics, Inc.Sarepta Therapeutics, Inc.
Active Organization-
Inactive Organization
Sarepta Therapeutics, Inc.Sarepta Therapeutics, Inc.Cook Medical LLCCook Medical LLCGlobal Therapeutics Pty Ltd.
License Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

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Related

1
Clinical Trials associated with AVI-5126
NCT00451256
/ TerminatedPhase 2
Clinical Study to Assess the Safety and Efficacy of ex-Vivo Vein Graft Exposure to AVI-5126 in Coronary Artery By-Pass Grafting to Reduce Clinical Graft Failure
100 Clinical Results associated with AVI-5126
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100 Translational Medicine associated with AVI-5126
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100 Patents (Medical) associated with AVI-5126
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100 Deals associated with AVI-5126
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Coronary Artery DiseasePhase 2
Ukraine
Sarepta Therapeutics, Inc.Sarepta Therapeutics, Inc.
01 Mar 2007
Graft dysfunctionPhase 2
Ukraine
Sarepta Therapeutics, Inc.Sarepta Therapeutics, Inc.
01 Mar 2007
Coronary RestenosisPhase 2
Germany
Global Therapeutics Pty Ltd.
-
Coronary RestenosisPhase 2
Poland
Sarepta Therapeutics, Inc.Sarepta Therapeutics, Inc.
-
Coronary RestenosisPhase 2
Ukraine
Sarepta Therapeutics, Inc.Sarepta Therapeutics, Inc.
-
Coronary RestenosisPhase 2-
Cook Medical LLCCook Medical LLC
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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