Last update 27 Sep 2025

PI-0824

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Peptide immunotherapy, PI 0824
Target
DSG3
Action
modulators
Mechanism
DSG3 modulators(desmoglein 3 modulators)
Therapeutic Areas
Skin and Musculoskeletal DiseasesImmune System DiseasesOther Diseases
Active Indication-
Inactive Indication
Acne VulgarisPemphigus
Originator Organization
Genzyme Corp.Genzyme Corp.
Active Organization-
Inactive Organization
Orphan Europe SARLOrphan Europe SARLPeptimmune, Inc.Peptimmune, Inc.
Genzyme Corp.Genzyme Corp.
License Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Related

1
Clinical Trials associated with PI-0824
NCT00063752
/ CompletedPhase 1
An Open-Label, Dose-Escalation, Phase I Clinical Study to Assess the Safety of PI-0824 in Patient With Pemphigus Vulgaris Requiring Daily Corticosteroid Therapy
100 Clinical Results associated with PI-0824
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100 Translational Medicine associated with PI-0824
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100 Patents (Medical) associated with PI-0824
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100 Deals associated with PI-0824
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External Link

KEGGWikiATCDrug Bank
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DB05516

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acne VulgarisPhase 2-
Genzyme Corp.Genzyme Corp.
-
Acne VulgarisPhase 2-
Orphan Europe SARLOrphan Europe SARL
-
PemphigusPhase 1
United States
Peptimmune, Inc.Peptimmune, Inc.
01 Jul 2003
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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