Last update 25 Oct 2025

SJ001008030

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
SJ001008030
Target
JAK2
Action
degraders
Mechanism
JAK2 degraders(Tyrosine-protein kinase JAK2 degraders)
Therapeutic Areas
NeoplasmsImmune System DiseasesSkin and Musculoskeletal Diseases
Active Indication
NeoplasmsRheumatoid Arthritis
Inactive Indication-
Originator Organization
Usona InstituteUsona Institute
Active Organization
Usona InstituteUsona Institute
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC42H43N13O7S
InChIKeyPURCRNBCKBOXFH-UHFFFAOYSA-N
CAS Registry-

Related

100 Clinical Results associated with SJ001008030
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100 Translational Medicine associated with SJ001008030
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100 Patents (Medical) associated with SJ001008030
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1
Literatures (Medical) associated with SJ001008030
10 Jun 2021ACS medicinal chemistry letters
PROTAC-Mediated Degradation of Janus Kinase as a Therapeutic Strategy for Cancer and Rheumatoid Arthritis
100 Deals associated with SJ001008030
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
United States
Usona InstituteUsona Institute
10 May 2021
Rheumatoid ArthritisPreclinical
United States
Usona InstituteUsona Institute
10 May 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Clinical Trial

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Approval

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Regulation

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