Last update 20 Mar 2025

BCMA-TGFβ CAR-T cells(Medical College of Wisconsin)

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms-
Target
BCMA x TGF-β
Action
modulators
Mechanism
BCMA modulators(B-cell maturation protein modulators), TGF-β modulators(Transforming growth factor beta modulators), Immunologic cytotoxicity
+ [1]
Therapeutic Areas
NeoplasmsImmune System DiseasesCardiovascular Diseases+ [1]
Active Indication
Multiple Myeloma
Inactive Indication-
Originator Organization
Medical College of WisconsinMedical College of Wisconsin
Active Organization
Medical College of WisconsinMedical College of Wisconsin
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with BCMA-TGFβ CAR-T cells(Medical College of Wisconsin)
NCT05976555
/ Not yet recruitingPhase 1IIT
Phase I Study of BCMA-TGF-BETA Insensitive Armored CAR T Cells in Patients with Relapsed And/or Refractory Multiple Myeloma
ChiCTR2100046374
/ RecruitingPhase 1/2IIT
To investigate the effectiveness and safety of up-front consolidation with BCMA-targeted CAR T-cell for newly diagnosed multiple myeloma
100 Clinical Results associated with BCMA-TGFβ CAR-T cells(Medical College of Wisconsin)
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100 Translational Medicine associated with BCMA-TGFβ CAR-T cells(Medical College of Wisconsin)
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100 Patents (Medical) associated with BCMA-TGFβ CAR-T cells(Medical College of Wisconsin)
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100 Deals associated with BCMA-TGFβ CAR-T cells(Medical College of Wisconsin)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Multiple MyelomaPhase 1-
Medical College of WisconsinMedical College of Wisconsin
01 Mar 2025
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Clinical Result

Indication
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Approval

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Regulation

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