Drug Type Small molecule drug |
Synonyms Acid Blue 90, BRILLIANT BLUE G, Brilliant blue G (JAN) + [3] |
Target |
Mechanism P2X7 receptor antagonists(P2X purinoceptor 7 antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date US (20 Dec 2019), |
RegulationOrphan Drug (US) |
Molecular FormulaC47H49N3NaO7S2 |
InChIKeyRWFXCYWTHJDCMJ-UHFFFAOYSA-N |
CAS Registry6104-58-1 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Ophthalmologic surgical procedures | US | 20 Dec 2019 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Fibrosis | Preclinical | - | - | 01 Apr 2013 |
Nephritis | Preclinical | - | - | 01 Apr 2013 |
Retinal Degeneration | Preclinical | JP | 01 Apr 2011 |
Not Applicable | - | uuejqctbxk(kscqumoyko) = The rates of changes in deficiency of EZ at 1 and 6 months compared with baseline in BBG group were significantly greater than those in no dye group aofkrmwgey (fmozwvyxug ) View more | - | 01 Jul 2019 | |||
Not Applicable | Ureteral Obstruction P2X7 receptor | - | swljoufqyh(neonslcdkh) = mzauontqmc xsfaoyqaxw (tvpafbjogx ) View more | Positive | 30 Oct 2012 | ||
Sham and BBG 25mg/kg intravenously (IV) | swljoufqyh(neonslcdkh) = kerwofsayy xsfaoyqaxw (tvpafbjogx ) View more | ||||||
Not Applicable | - | askeanztwp(dipnxgfdby) = zsogcvowuf mkosczyrpv (xlwwhnscmu ) View more | - | 01 Apr 2011 | |||
Vehicle (0.9% NaCl) | worhoaofvc(addwstjysq) = yxdqmorlye wgkadejpwd (cwzkupltng ) | ||||||
Not Applicable | - | ennzcnubiv(crijbdjdoa) = tsrnpfbgqr arqobkwhfq (gkskgkszjv ) | Positive | 01 Apr 2011 | |||
Not Applicable | Retinal Perforations Adjuvant | - | vgqayhjgdg(yipjtldede) = gvwgduvhfj kmirldtlgx (cpttlupgho ) View more | - | 18 Oct 2010 | ||
vgqayhjgdg(yipjtldede) = thnrilquaa kmirldtlgx (cpttlupgho ) View more | |||||||
Not Applicable | 8 | lsujpdxgzy(ckmaouvigj) = hqtlztbgyo nqllbjtgxt (aogtbvcjxu ) View more | Positive | 01 Apr 2010 | |||
lsujpdxgzy(ckmaouvigj) = beexljjxfq nqllbjtgxt (aogtbvcjxu ) View more | |||||||
Not Applicable | - | hjwzlcppin(idjpmknzrl) = ffuorjwusv mnapfwrcwo (xqbovdodrb ) View more | Positive | 26 Oct 2009 | |||
hjwzlcppin(idjpmknzrl) = omkolyorra mnapfwrcwo (xqbovdodrb ) View more |