Delving into the Latest Updates on Cetirizine Amidine Sodium with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

Ceftriamidine Sodium, BYS 02, BYS-02

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Target

PBPs

Action

inhibitors

Mechanism

PBPs inhibitors(Bacterial penicillin-binding protein inhibitors)

Therapeutic Areas

Infectious DiseasesRespiratory Diseases

Active Indication

Community-acquired bacterial pneumonia

Inactive Indication-

Originator Organization

Guangzhou Baiyunshan Pharmaceutical Holdings Co., Ltd.

Active Organization

Guangdong South China New Drug Creation Center

Guangzhou Baiyunshan General Pharmaceutical Factory

Inactive Organization-

Drug Highest PhasePhase 2

First Approval Date-

RegulationSpecial Review Project (China)

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主要目的：评估在社区获得性细菌性肺炎患者多次使用注射用头孢嗪脒钠后的药代动力学/药效动力学特征。次要目的：评估在社区获得性细菌性肺炎患者多次使用注射用头孢嗪脒钠后的安全性。评估在社区获得性细菌性肺炎患者多次使用注射用头孢嗪脒钠后的初步有效性。

[Translation]

Primary objective: To evaluate the pharmacokinetic/pharmacodynamic characteristics of cefuroxime sodium for injection after multiple administration in patients with community-acquired bacterial pneumonia. Secondary objective: To evaluate the safety of cefuroxime sodium for injection after multiple administration in patients with community-acquired bacterial pneumonia. To evaluate the preliminary effectiveness of cefuroxime sodium for injection after multiple administration in patients with community-acquired bacterial pneumonia.

Start Date18 Oct 2024

Sponsor / Collaborator

Guangdong South China New Drug Creation Center

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ChiCTR2400086640

/ SuspendedPhase 2IIT

Pharmacokinetic and pharmacodynamic study of Ceftriamidine Sodium for Injection in patients with community-acquired bacterial pneumonia

Start Date12 Jul 2024

Sponsor / Collaborator

Xiangya Hospital Central South University

CTR20230788

/ CompletedPhase 1

注射用头孢嗪脒钠在中国健康受试者中多次给药的安全性、耐受性及药代动力学研究

[Translation] Safety, tolerability and pharmacokinetics of cefuroxime sodium for injection after repeated administration in Chinese healthy subjects

主要目的：评估健康受试者多次使用注射用头孢嗪脒钠后的安全性和耐受性。次要目的：评估健康受试者多次使用注射用头孢嗪脒钠后的药代动力学特性。

[Translation]

Primary objective: To evaluate the safety and tolerability of cefuroxime sodium for injection after multiple administration in healthy subjects. Secondary objective: To evaluate the pharmacokinetic properties of cefuroxime sodium for injection after multiple administration in healthy subjects.

Start Date19 Mar 2023

Sponsor / Collaborator

Guangdong South China New Drug Creation Center

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100 Clinical Results associated with Cetirizine Amidine Sodium

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100 Translational Medicine associated with Cetirizine Amidine Sodium

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100 Patents (Medical) associated with Cetirizine Amidine Sodium

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100 Deals associated with Cetirizine Amidine Sodium

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R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Community-acquired bacterial pneumonia	Phase 2	China	Guangdong South China New Drug Creation Center	18 Oct 2024
Community-acquired bacterial pneumonia	Phase 2	China	Guangzhou Baiyunshan General Pharmaceutical Factory	18 Oct 2024