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Last update 19 Apr 2025
PROTAC ER degraders 45 (University of Michigan)
Last update 19 Apr 2025
Overview
Basic Info
Drug Type Proteolysis-targeting chimeras (PROTAC) |
Synonyms- |
Target |
Action degraders |
Mechanism ESR1 degraders(Estrogen receptor alpha degraders) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhasePendingPreclinical |
First Approval Date- |
Regulation- |
Structure/Sequence
Molecular FormulaC54H64N4O8S |
InChIKeySCXSSSMBXFITNZ-XRXXYBJXSA-N |
CAS Registry- |
R&D Status
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Estrogen receptor positive breast cancer | Preclinical | United States | 18 Jan 2019 |
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Clinical Result
Clinical Result
Indication
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