HXN-5003

The goal of this intervention study is to evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of HXN5003 in Healthy Participants.The main parameters it aims to answer are:
1. Does a single dose of HXN5003 in healthy participants impact the safety, tolerability and pharmacokinetic profiles?
2. Will immunogenicity of HXN5003 in healthy participants be altered? This study will be compared against a Placebo which contains the same inactive ingredients as those of HXN5003, but without the active ingredient.

Part A健康人单剂量递增探索阶段：评估HXN5003注射液在健康参与者中单次给药的安全性、耐受性、药代动力学特征和免疫原性。 Part B中重度特应性皮炎患者多次给药剂量递增探索阶段：评估HXN5003注射液在中重度特应性皮炎患者中多次给药的安全性、耐受性、药代动力学特征、初步有效性和免疫原性。