Last update 15 Dec 2025

PRA-523

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Small Molecules to Antagonize 5HT7 Receptors for Crohn’s Disease and Ulcerative Colitis(PRAEVENTIX), PRA 523, PRA523
Target
5-HT7 receptor
Action
antagonists
Mechanism
5-HT7 receptor antagonists(Serotonin 7 (5-HT7) receptor antagonists)
Therapeutic Areas
Skin and Musculoskeletal Diseases
Active Indication
Pruritus
Inactive Indication
Colitis, UlcerativeCrohn Disease
Originator Organization
Praeventix, Inc.Praeventix, Inc.
Active Organization
Praeventix, Inc.Praeventix, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with PRA-523
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100 Translational Medicine associated with PRA-523
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100 Patents (Medical) associated with PRA-523
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100 Deals associated with PRA-523
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
PruritusPreclinical
United States
Praeventix, Inc.Praeventix, Inc.
01 Apr 2025
Colitis, UlcerativePreclinical
United States
Praeventix, Inc.Praeventix, Inc.
23 Jul 2019
Crohn DiseasePreclinical
United States
Praeventix, Inc.Praeventix, Inc.
23 Jul 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Core Patent

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Clinical Trial

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Approval

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Regulation

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