Last update 21 Jun 2025

LY-3875383

Overview

Basic Info

Drug Type
siRNA
Synonyms
APOC3 siRNA(Eli Lilly and Company), APOC3 targeting small interfering RNA(Eli Lilly and Company), LY 3875383
+ [1]
Target
APOC3
Action
inhibitors
Mechanism
APOC3 inhibitors(Apolipoprotein C-III inhibitors)
Therapeutic Areas
Endocrinology and Metabolic Disease
Active Indication-
Inactive Indication
Hypertriglyceridemia
Originator Organization
Eli Lilly & Co.Eli Lilly & Co.
Active Organization-
Inactive Organization
Eli Lilly & Co.Eli Lilly & Co.
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Structure/Sequence

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Related

1
Clinical Trials associated with LY-3875383
NCT05609825
/ TerminatedPhase 1
A Single-Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY3875383 in Healthy Participants and Participants With Hypertriglyceridemia
100 Clinical Results associated with LY-3875383
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100 Translational Medicine associated with LY-3875383
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100 Patents (Medical) associated with LY-3875383
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100 Deals associated with LY-3875383
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
HypertriglyceridemiaPhase 1
Singapore
Eli Lilly & Co.Eli Lilly & Co.
14 Nov 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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