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Last update 24 May 2025
CLDN18.2-ADC (Fortvita Biologics)
Last update 24 May 2025
Overview
Basic Info
Drug Type Antibody drug conjugate (ADC) |
Synonyms Antibody-drug conjugate (ADC) consisting of a fully human, Fc-silenced IgG1 anti-claudin 18.2 monoclonal antibody, a cleavable linker, and exatecan, a topoisomerase I inhibitor (Fortvita Biologics) |
Target |
Action inhibitors |
Mechanism CLDN18.2 inhibitors(Claudin 18.2 inhibitors), TOP1 inhibitors(DNA topoisomerase I inhibitors) |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePreclinical |
First Approval Date- |
RegulationOrphan Drug (United States) |
Structure/Sequence
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R&D Status
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Pancreatic Cancer | Preclinical | United States | 24 Feb 2025 |
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Biosimilar
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