Delving into the Latest Updates on Aleeto with Synapse

Overview

Basic Info

Drug Type

Protein drugs

Synonyms-

Target-

Mechanism-

Therapeutic Areas

Nervous System DiseasesCardiovascular DiseasesEndocrinology and Metabolic Disease+ [1]

Active Indication

Acute Ischemic StrokeAmyotrophic Lateral SclerosisMultiple System Atrophy

Inactive Indication-

Originator Organization

Beijing Tiantan Hospital

Active Organization

Beijing Tiantan Hospital

Inactive Organization-

Drug Highest PhasePhase 2

First Approval Date-

Regulation-

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This study is a prospective, double-blind, 1:1:1 randomized controlled study aimed at evaluating the efficacy and safety of Aleeto treatment compared to placebo in improving the NIHSS score at 90 days in patients with moderate to severe acute ischemic stroke. It also aims to explore the neuroprotective effects of Aleeto in moderate to severe acute ischemic stroke and provide data support and evidence for future clinical trials and evidence-based medicine.

Start Date31 Dec 2024

Sponsor / Collaborator

Beijing Tiantan Hospital

NCT06765733

/ Not yet recruitingEarly Phase 1IIT

The Study of Safety and Preliminary Efficacy of Aleeto in Patients with MultIple System Atrophy

This is a single-center, prospective, randomized, open-label, blinded outcome assessment (PROBE) study. At the end of the PROBE study, patients who have completed the study may opt to enter the open-label extension (OLE) study. The objective of the study is to evaluate the safety, tolerability and potential preliminary efficacy of Aleeto in the treatment of patients with multiple system atrophy (MSA).

Start Date31 Dec 2024

Sponsor / Collaborator

Beijing Tiantan Hospital

ChiCTR2400082310

/ SuspendedPhase 1IIT

Single-arm, open-label, single-center clinical trial of the safety and preliminary efficacy of ALEETO in the treatment of mild to moderate Alzheimer's disease

Start Date26 Mar 2024

Sponsor / Collaborator-

100 Clinical Results associated with Aleeto

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100 Translational Medicine associated with Aleeto

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100 Patents (Medical) associated with Aleeto

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100 Deals associated with Aleeto

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R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Acute Ischemic Stroke	Phase 2	CN	Beijing Tiantan Hospital	31 Dec 2024
Multiple System Atrophy	Phase 1	CN	Beijing Tiantan Hospital	31 Dec 2024
Amyotrophic Lateral Sclerosis	Phase 1	CN	Beijing Tiantan Hospital	15 Dec 2023