Last update 27 Dec 2024

MRJF22

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(±)-MRJF 22, (±)-MRJF22
Target
HDACs x σ1 receptor x σ2 receptor
Mechanism
HDAC inhibitors(Histone deacetylase inhibitors), σ1 receptor antagonists(Sigma opioid receptor antagonists), σ2 receptor agonists(Sigma-2 receptor agonists)
Therapeutic Areas
Cardiovascular DiseasesCongenital DisordersEndocrinology and Metabolic Disease+ [1]
Active Indication
Proliferative retinopathy with diabetes mellitusWet age-related macular degeneration
Inactive Indication-
Originator Organization
University of CataniaUniversity of Catania
Active Organization
University of CataniaUniversity of Catania
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure

Molecular FormulaC29H39ClFNO3
InChIKeyZMMTZQWVQFDIBG-UHFFFAOYSA-N
CAS Registry2044017-78-7

Related

100 Clinical Results associated with MRJF22
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100 Translational Medicine associated with MRJF22
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100 Patents (Medical) associated with MRJF22
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100 Deals associated with MRJF22
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Proliferative retinopathy with diabetes mellitusPreclinical
IT
University of CataniaUniversity of Catania
25 Oct 2016
Wet age-related macular degenerationPreclinical
IT
University of CataniaUniversity of Catania
25 Oct 2016
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Clinical Result

Indication
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Approval

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Regulation

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