Last update 06 Dec 2025

ESR-114

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ESR 114
Target
RORγt
Action
inhibitors
Mechanism
RORγt inhibitors(RAR-related orphan receptor gamma 2 inhibitors)
Therapeutic Areas
Immune System DiseasesSkin and Musculoskeletal Diseases
Active Indication-
Inactive Indication
Plaque psoriasis
Originator Organization
Escalier Biosciences BV
Active Organization-
Inactive Organization
Escalier Biosciences BV
License Organization-
Drug Highest PhasePendingPhase 1/2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with ESR-114
NCT03630939
/ CompletedPhase 1/2
A Multicenter, Double-Blind, Randomized, Vehicle-Controlled Phase 1/2a Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of Topical ESR-114 Gel in Subjects With Plaque Psoriasis
100 Clinical Results associated with ESR-114
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100 Translational Medicine associated with ESR-114
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100 Patents (Medical) associated with ESR-114
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100 Deals associated with ESR-114
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Plaque psoriasisPhase 2
United States
Escalier Biosciences BV
09 Aug 2018
Plaque psoriasisPhase 2
Canada
Escalier Biosciences BV
09 Aug 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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