Last update 25 Jul 2026

DS1025a

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms-
Target
IL2RA x Top I
Action
modulators, inhibitors
Mechanism
IL2RA modulators(Interleukin-2 receptor alpha chain modulators), TOP1 inhibitors(DNA topoisomerase I inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid NeoplasmMetastatic Solid Tumor
Inactive Indication-
Originator Organization
Daiichi Sankyo Co., Ltd.Daiichi Sankyo Co., Ltd.
Active Organization
Daiichi Sankyo Co., Ltd.Daiichi Sankyo Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC26H24FN3O6
InChIKeyPLXLYXLUCNZSAA-QLXKLKPCSA-N
CAS Registry1599440-33-1
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Related

1
Clinical Trials associated with DS1025a
NCT07681882
/ Not yet recruitingPhase 1
A Phase 1, Multicenter, Open-label, First-in-Human Trial of DS1025a in Participants With Advanced Solid Tumors
100 Clinical Results associated with DS1025a
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100 Translational Medicine associated with DS1025a
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100 Patents (Medical) associated with DS1025a
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100 Deals associated with DS1025a
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
Japan
Daiichi Sankyo Co., Ltd.Daiichi Sankyo Co., Ltd.
03 Aug 2026
Metastatic Solid TumorPhase 1
Japan
Daiichi Sankyo Co., Ltd.Daiichi Sankyo Co., Ltd.
03 Aug 2026
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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