Last update 15 Jul 2026

LZ001

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
LZ 001, LZ-001, LZ001
Target
NTRK x ROS1
Action
inhibitors
Mechanism
NTRK inhibitors(Neurotrophic tyrosine kinase receptor inhibitors), ROS1 inhibitors(Proto-oncogene tyrosine-protein kinase ROS inhibitors)
Therapeutic Areas
NeoplasmsNervous System Diseases
Active Indication-
Inactive Indication
Advanced Malignant Solid NeoplasmCentral Nervous System NeoplasmsPD-L1 positive Solid Tumors+ [1]
Originator Organization
Livzon Pharmaceutical Group, Inc.Livzon Pharmaceutical Group, Inc.
Active Organization-
Inactive Organization
Livzon Pharmaceutical Group, Inc.Livzon Pharmaceutical Group, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with LZ001
CTR20221852
/ TerminatedPhase 1
评价LZ001单药治疗携带NTRK1/2/3、ROS1或ALK基因融合晚期实体瘤患者中的安全性、耐受性、药代动力学特征和疗效I期研究
[Translation] Phase I study to evaluate the safety, tolerability, pharmacokinetic characteristics and efficacy of LZ001 monotherapy in patients with advanced solid tumors harboring NTRK1/2/3, ROS1 or ALK gene fusions
100 Clinical Results associated with LZ001
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100 Translational Medicine associated with LZ001
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100 Patents (Medical) associated with LZ001
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100 Deals associated with LZ001
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
China
Livzon Pharmaceutical Group, Inc.Livzon Pharmaceutical Group, Inc.
13 Sep 2022
Central Nervous System NeoplasmsPhase 1
China
Livzon Pharmaceutical Group, Inc.Livzon Pharmaceutical Group, Inc.
13 Sep 2022
PD-L1 positive Solid TumorsPhase 1
China
Livzon Pharmaceutical Group, Inc.Livzon Pharmaceutical Group, Inc.
13 Sep 2022
Solid tumorPhase 1
China
Livzon Pharmaceutical Group, Inc.Livzon Pharmaceutical Group, Inc.
13 Sep 2022
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Clinical Trial

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Approval

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Regulation

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