Last update 04 Dec 2025

CE-245677

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CE 245677
Target
NTRK x Tie-2
Action
inhibitors, antagonists
Mechanism
NTRK inhibitors(Neurotrophic tyrosine kinase receptor inhibitors), Tie-2 antagonists(TEK receptor tyrosine kinase antagonists)
Therapeutic Areas
NeoplasmsNervous System DiseasesOther Diseases
Active Indication-
Inactive Indication
Inflammatory painNeoplasms
Originator Organization
Pfizer Inc.Pfizer Inc.
Active Organization-
Inactive Organization
Pfizer Inc.Pfizer Inc.
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC24H22Cl2N6O3
InChIKeyVFCRSIORGUNNGT-UHFFFAOYSA-N
CAS Registry717899-97-3

Related

100 Clinical Results associated with CE-245677
Login to view more data
100 Translational Medicine associated with CE-245677
Login to view more data
100 Patents (Medical) associated with CE-245677
Login to view more data
100 Deals associated with CE-245677
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPhase 1-
Pfizer Inc.Pfizer Inc.
-
Inflammatory painPreclinical
United Kingdom
Pfizer Inc.Pfizer Inc.
-
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free