Last update 13 Dec 2025

CT-0181

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms
CT0181 humanised anti GPC3 autogenous T Cell injection - CARSgen, CT 0181, CT-0181
Target
GPC3
Action
inhibitors
Mechanism
GPC3 inhibitors(Glypican-3 inhibitors), Immunologic cytotoxicity, T lymphocyte replacements
Therapeutic Areas
NeoplasmsDigestive System Disorders
Active Indication-
Inactive Indication
Advanced Hepatocellular Carcinoma
Originator Organization
CARsgen Therapeutics Co. Ltd.CARsgen Therapeutics Co. Ltd.
Active Organization-
Inactive Organization
CARsgen Therapeutics Co. Ltd.CARsgen Therapeutics Co. Ltd.
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with CT-0181
NCT05344664
/ Unknown statusPhase 1IIT
Safety and Efficacy of Novel GPC3 CAR-T Cells in the Treatment of Hepatocellular Carcinoma Exploratory Clinical Studies
NCT04973098
/ Unknown statusPhase 1IIT
An Open-Label, Dose Escalation/Dose Exploration, Phase I Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single/Multiple Infusion of CT0181 Injection in Patients With Advanced Hepatocellular Carcinoma
100 Clinical Results associated with CT-0181
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100 Translational Medicine associated with CT-0181
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100 Patents (Medical) associated with CT-0181
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100 Deals associated with CT-0181
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Hepatocellular CarcinomaPhase 1
China
CARsgen Therapeutics Co. Ltd.CARsgen Therapeutics Co. Ltd.
05 Aug 2021
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Clinical Result

Indication
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Evaluation
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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