Last update 13 Nov 2025

CGB-1001

Overview

Basic Info

Drug Type
Antibody oligonucleotide conjugates
Synonyms
CGB1001
Target
DMPK x TfR1
Action
inhibitors, antagonists
Mechanism
DMPK inhibitors(DM1 protein kinase inhibitors), TfR1 antagonists(Transferrin receptor protein 1 antagonists)
Therapeutic Areas
Nervous System DiseasesCongenital DisordersSkin and Musculoskeletal Diseases+ [1]
Active Indication
Myotonic Dystrophy
Inactive Indication-
Originator Organization
ChainGen Biopharma Ltd.
Active Organization
ChainGen Biopharma Ltd.
Inactive Organization-
License Organization-
Drug Highest PhaseClinical
First Approval Date-
RegulationOrphan Drug (United States)

Structure/Sequence

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Related

1
Clinical Trials associated with CGB-1001
ChiCTR2500097222
/ Not yet recruitingNot ApplicableIIT
An open-label, dose-escalation clinical study evaluating the safety and tolerability of CGB1001 in patients with myotonic dystrophy type 1 (DM1)
100 Clinical Results associated with CGB-1001
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100 Translational Medicine associated with CGB-1001
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100 Patents (Medical) associated with CGB-1001
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100 Deals associated with CGB-1001
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Myotonic DystrophyClinical
China
ChainGen Biopharma Ltd.
14 Feb 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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